IDRA-21
Cognitive · Ampakine
Tier D
What this is
Cortex Pharmaceuticals-era compound. Primate cognition data (Baboons — Buccafusco) but no human trials. Typical ampakine concerns: seizure threshold lowering with chronic or high-dose use.
Mechanism
Benzothiadiazide ampakine; positive allosteric modulator of AMPA receptors; slows receptor desensitization; parent compound of the benzothiadiazide ampakine class
Dose & route
No established human dosing
Citations
- https://pubmed.ncbi.nlm.nih.gov/9216180/
- https://pubmed.ncbi.nlm.nih.gov/11164771/
- https://pubmed.ncbi.nlm.nih.gov/15582680/
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