Rankings / Hormones & Endocrine
Other aromatase inhibitors (letrozole / exemestane / formestane / arimistane)
Hormones & Endocrine · Aromatase inhibitor
Tier C+
What this is
WADA coverage: 2-Androstenol, 2-Androstenone, alpha-naphthoflavone/7,8-benzoflavone, 3-Androstenol, 3-Androstenone, 6-OXO, aminoglutethimide, anastrozole, androstatrienedione/ATD, arimistane, exemestane, formestane, letrozole and testolactone. Anastrozole remains its own row; this row covers the remaining WADA aromatase-inhibitor class.
Mechanism
Aromatase inhibitors lower estrogen synthesis and are used medically in estrogen-receptor-positive breast cancer; biohacker/bodybuilding use aims to alter testosterone:estradiol balance.
Dose & route
Clinical oncology dosing varies; no healthy optimization dose
Citations
- https://www.ncbi.nlm.nih.gov/books/NBK305894/
- https://www.wada-ama.org/en/resources/2026-prohibited-list
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This is an independent synthesis of published research by a non-clinician. Scores are opinions supported by citations, not prescriptions. See the full disclaimer and methodology for how this score was produced and what it does and doesn't mean.