Rankings / Hormones & Endocrine
Other SERMs / anti-estrogens (tamoxifen / raloxifene / fulvestrant)
Hormones & Endocrine · SERM / estrogen receptor modulator
Tier C+
What this is
WADA coverage: bazedoxifene, clomifene/clomiphene, cyclofenil, elacestrant, fulvestrant, ospemifene, raloxifene, tamoxifen and toremifene. Clomiphene and enclomiphene keep their individual rows; this row covers the broader WADA anti-estrogen class.
Mechanism
SERMs and anti-estrogens modulate estrogen receptor signaling or estrogen feedback; bodybuilding use often targets post-cycle HPG-axis recovery or gynecomastia control.
Dose & route
Clinical dosing varies by indication; no healthy optimization dose
Citations
- https://www.ncbi.nlm.nih.gov/books/NBK305894/
- https://www.wada-ama.org/en/resources/2026-prohibited-list
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This is an independent synthesis of published research by a non-clinician. Scores are opinions supported by citations, not prescriptions. See the full disclaimer and methodology for how this score was produced and what it does and doesn't mean.