Yellow oleander-adulterated weight-loss supplements

What this is

FDA updated the safety alert on March 11, 2026 after adding another product found to contain toxic yellow oleander. The issue is substitution/adulteration: products labeled as tejocote root or Brazil seed may actually contain Thevetia peruviana. This is a high-signal toxin row because it sits at the intersection of weight-loss supplements and acute cardiac-glycoside poisoning.

Mechanism

Yellow oleander (Thevetia peruviana) contains cardiac glycosides that can disrupt cardiac conduction and trigger severe GI, neurologic, and cardiovascular toxicity.

Dose & route

Avoid tejocote/Brazil seed weight-loss supplements from unverified sellers; dispose of products on FDA alert list

Citations

• https://www.fda.gov/food/alerts-advisories-safety-information/fda-issues-warning-about-certain-supplements-substituted-toxic-yellow-oleander

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