Rankings / Toxins
Toxins
Air, water, food, and lifestyle exposures with evidence for harm. Everything here scores poorly by design — the "intervention" is reducing exposure.
| # | Compound | Ev | Mag | Prev | Priority · Score |
|---|---|---|---|---|---|
| 1 | Chronic sleep deprivation Lifestyle | 10.0 | 10.0 | 10.0 | CRITICAL 10.0 |
| 2 | Loneliness / social isolation Lifestyle | 10.0 | 10.0 | 10.0 | CRITICAL 10.0 |
| 3 | Sedentary behavior / sitting Lifestyle | 10.0 | 10.0 | 10.0 | CRITICAL 10.0 |
| 4 | Tobacco smoke (direct / secondhand) Combustion complex | 10.0 | 10.0 | 10.0 | CRITICAL 10.0 |
| 5 | Lead Heavy metal / neurotoxicant | 10.0 | 10.0 | 8.0 | CRITICAL 9.4 |
| 6 | PM2.5 (fine particulate matter) Air pollution | 10.0 | 10.0 | 8.0 | CRITICAL 9.4 |
| 7 | PFAS (PFOA / PFOS / GenX) Forever chemicals | 8.0 | 10.0 | 8.0 | CRITICAL 8.8 |
| 8 | Benzene Volatile organic compound | 10.0 | 8.0 | 8.0 | CRITICAL 8.6 |
| 9 | Chronic psychological stress Lifestyle | 8.0 | 8.0 | 10.0 | CRITICAL 8.6 |
| 10 | Nitrite poppers (amyl/isobutyl nitrite products) Recreational inhalant / vasodilator | 8.0 | 8.0 | 10.0 | CRITICAL 8.6 |
| 11 | Yellow oleander-adulterated weight-loss supplements Botanical adulterant / cardiac glycoside | 8.0 | 8.0 | 10.0 | CRITICAL 8.6 |
| 12 | Alcohol (ethanol) Neurotoxic psychoactive | 10.0 | 10.0 | 5.0 | CRITICAL 8.5 |
| 13 | Radon Radioactive gas | 10.0 | 10.0 | 5.0 | CRITICAL 8.5 |
| 14 | DMAA / DMHA stimulant adulterants Illicit stimulant adulterant | 8.0 | 8.0 | 8.0 | HIGH 8.0 |
| 15 | Formaldehyde VOC / IARC Group 1 | 8.0 | 8.0 | 8.0 | HIGH 8.0 |
| 16 | Nitrous oxide (recreational inhalation) Recreational inhalant / dissociative gas | 8.0 | 8.0 | 8.0 | HIGH 8.0 |
| 17 | Organophosphate pesticides (chlorpyrifos / malathion) Acetylcholinesterase inhibitor | 8.0 | 8.0 | 8.0 | HIGH 8.0 |
| 18 | TCE (trichloroethylene) Chlorinated solvent | 8.0 | 8.0 | 8.0 | HIGH 8.0 |
| 19 | NO2 (nitrogen dioxide) Air pollution | 8.0 | 8.0 | 6.5 | HIGH 7.6 |
| 20 | Ozone (tropospheric) Air pollution | 8.0 | 8.0 | 6.5 | HIGH 7.6 |
| 21 | Aflatoxins Mycotoxin | 10.0 | 10.0 | 1.0 | HIGH 7.3 |
| 22 | Arsenic Metalloid / IARC Group 1 | 8.0 | 8.0 | 5.0 | HIGH 7.1 |
| 23 | Phthalates (DEHP / DBP / BBP / DEP) Endocrine disruptor | 7.0 | 6.5 | 5.0 | MODERATE 6.2 |
| 24 | Fluoride (high-dose) Controversial | 8.0 | 8.0 | 1.0 | MODERATE 5.9 |
| 25 | Mercury (methylmercury) Heavy metal / neurotoxicant | 8.0 | 5.0 | 5.0 | MODERATE 5.9 |
| 26 | Blue light (evening artificial light at night) Circadian disruptor | 8.0 | 5.0 | 3.0 | MODERATE 5.3 |
| 27 | Cadmium Heavy metal / nephrotoxicant | 8.0 | 5.0 | 3.0 | MODERATE 5.3 |
| 28 | PAHs (polycyclic aromatic hydrocarbons — grilled meats, air) Combustion carcinogen | 8.0 | 5.0 | 3.0 | MODERATE 5.3 |
| 29 | PBDEs (polybrominated diphenyl ethers) Flame retardant | 8.0 | 5.0 | 3.0 | MODERATE 5.3 |
| 30 | Neonicotinoids (imidacloprid / clothianidin) Neurotoxic insecticide | 8.0 | 5.0 | 1.0 | MODERATE 4.7 |
| 31 | Acrylamide (high-heat cooking) Maillard byproduct | 6.0 | 3.5 | 5.0 | MODERATE 4.7 |
| 32 | BPA / BPS / BPF (bisphenols) Endocrine disruptor | 6.0 | 5.0 | 3.0 | MODERATE 4.7 |
| 33 | DBPs (disinfection byproducts — trihalomethanes, haloacetic acids) Chlorination byproducts | 6.0 | 3.5 | 3.0 | MODERATE 4.1 |
| 34 | Ochratoxin A Mycotoxin | 6.0 | 3.5 | 3.0 | MODERATE 4.1 |
| 35 | Triclosan / triclocarban Antimicrobial | 6.0 | 3.5 | 3.0 | MODERATE 4.1 |
| 36 | EMF / RF exposure (cell phones, Wi-Fi) Non-ionizing radiation | 4.5 | 4.0 | 3.0 | LOW 3.9 |
| 37 | Glyphosate (Roundup) Broad-spectrum herbicide | 3.0 | 5.0 | 3.0 | LOW 3.8 |
| 38 | Parabens (methyl / propyl / butyl) Preservative / weak estrogen | 4.5 | 3.5 | 3.0 | LOW 3.7 |
| 39 | Microplastics / nanoplastics Emerging contaminant | 3.0 | 4.0 | 3.0 | LOW 3.4 |
| 40 | Aluminum Widespread metal | 4.5 | 3.5 | 1.0 | LOW 3.1 |