Rankings / Longevity
Longevity — Supplements
NAD+ precursors, alpha-ketoglutarate, astaxanthin, sulforaphane, GHK-Cu, tretinoin — the over-the-counter longevity supplement aisle.
| # | Compound | Ev | Bn | Sf | Grade · Score |
|---|---|---|---|---|---|
| 1 | Tretinoin (all-trans retinoic acid) Retinoid — RAR agonist | 10.0 | 10.0 | 5.0 | A 8.0 |
| 2 | Alpha-ketoglutarate (Ca-AKG) TCA cycle intermediate | 6.0 | 5.0 | 9.0 | B+ 7.1 |
| 3 | Astaxanthin Carotenoid antioxidant | 6.0 | 5.0 | 9.0 | B+ 7.1 |
| 4 | Glycine (longevity / metabolic) Amino acid / methionine restriction mimetic | 6.0 | 5.0 | 9.0 | B+ 7.1 |
| 5 | Glycine + NAC (GlyNAC) Amino acid combo | 6.0 | 5.0 | 9.0 | B+ 7.1 |
| 6 | NAD+ / NMN / NR NAD+ precursor | 6.0 | 5.0 | 9.0 | B+ 7.1 |
| 7 | Sulforaphane Nrf2 activator | 6.0 | 5.0 | 9.0 | B+ 7.1 |
| 8 | 17-alpha estradiol Non-feminizing estrogen | 2.0 | 5.0 | 7.0 | C- 4.5 |
| 9 | GDF11 Circulating factor | 2.0 | 5.0 | 5.0 | D+ 3.7 |
| 10 | Klotho Anti-aging protein | 2.0 | 5.0 | 5.0 | D+ 3.7 |
| 11 | C60 (carbon 60 / buckminsterfullerene) Fullerene / antioxidant | 3.0 | 2.0 | 4.0 | D 3.3 |
| 12 | Plasma exchange / young plasma Dilutional therapeutic | 2.0 | 5.0 | 3.5 | D 3.1 |
| 13 | Yamanaka factors / partial reprogramming Epigenetic reprogramming | 2.0 | 5.0 | 3.5 | D 3.1 |